<?xml version="1.0" encoding="UTF-8"?><DetectedIssue xmlns="http://hl7.org/fhir"><id value="ddi"/><meta><tag><system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/><code value="HTEST"/><display value="vyIqsFjoUXyqSN"/></tag></meta><text><status value="generated"/><div xmlns="http://www.w3.org/1999/xhtml"><p><b>Severity: High</b> - Risk of internal bleeding</p><p>Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding.</p><ul><li><a href="MedicationStatement/tylenol">500 mg Acetaminophen tablet 1/day, PRN since 2010</a></li><li><a href="MedicationRequest/warfarin">Warfarin 1 MG TAB prescribed Jan. 5, 2014</a></li></ul><p>Mitigation: Jan 5, 2014 by Dr. Adam Careful: </p><p>Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring</p></div></text><status value="final"/><code><coding><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><code value="DRG"/><display value="jAZczF2QQo1Ey3"/></coding></code><severity value="high"/><identifiedDateTime value="2014-01-05"/><author><reference value="Device/software"/></author><implicated><reference value="MedicationStatement/example001"/><display value="XepTyUjBqfKRbLZGy"/></implicated><implicated><reference value="MedicationRequest/medrx0331"/><display value="T0ZSf0algzeb"/></implicated><detail value="Risk of internal bleeding.  Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding."/><mitigation><action><coding><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><code value="13"/><display value="KHmRvGYhDIPOUH"/></coding><text value="4JwnXAlRkMCKVZYj"/></action><date value="2014-01-05"/><author><reference value="Practitioner/example"/><display value="9f9y0rqMWw32"/></author></mitigation></DetectedIssue>