<?xml version="1.0" encoding="UTF-8"?><DetectedIssue xmlns="http://hl7.org/fhir"><id value="ddc4b4d4-bc5a-4ce6-b558-0ce631800a8e"/><meta><versionId value="1"/><lastUpdated value="2022-02-17T17:34:52.710+08:00"/><tag><system value="http://terminology.hl7.org/CodeSystem/v3-ActReason"/><code value="HTEST"/><display value="test health data"/></tag></meta><status value="final"/><code><coding><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><code value="DRG"/><display value="Drug Interaction Alert"/></coding></code><severity value="high"/><identifiedDateTime value="2014-01-05T08:00:00+08:00"/><author><reference value="Device/software"/></author><implicated><reference value="MedicationStatement/example001"/><display value="500 mg Acetaminophen tablet 1/day, PRN since 2010"/></implicated><implicated><reference value="MedicationRequest/medrx0331"/><display value="Warfarin 1 MG TAB prescribed Jan. 15, 2015"/></implicated><detail value="Risk of internal bleeding.  Those who take acetaminophen along with the widely used blood-thinning drug warfarin may face the risk of serious internal bleeding. People on warfarin who take acetaminophen for at least seven days in a row should be closely watched for bleeding."/><mitigation><action><coding><system value="http://terminology.hl7.org/CodeSystem/v3-ActCode"/><code value="13"/><display value="Stopped Concurrent Therapy"/></coding><text value="Asked patient to discontinue regular use of Tylenol and to consult with clinician if they need to resume to allow appropriate INR monitoring"/></action><date value="2014-01-05T08:00:00+08:00"/><author><reference value="Practitioner/example"/><display value="Dr. Adam Careful"/></author></mitigation></DetectedIssue>